Side Effect from medication and specialty drugs

Commonly Requested Formulas for Patients with Mouth Sores/Mucositis

Stanford Modified Mouthwash (MucoLox™)
Misoprostol/Diphenhydramine HCl/Lidocaine HCl Oral Rinse (MucoLox™)
Misoprostol/Ketoconazole/Tetracycline HCl/Triamcinolone Acetonide/Chlorpheniramine Maleate/Deoxy-D-Glucose Oral Rinse (MucoLox™)
Beta Glucan/Dexpanthenol/Vitamin E Acetat Oral Rinse (MucoLox™)
Dexamethasone/Tetracycline HCl/Nystatin/Diphenhydramine HCl Mouthwash (MucoLox™)
Stanford Mouthwash (MucoLox™)

Commonly Requested Formulas for Patients with a Headache

Sumatriptan/Tramadol HCl/Gabapentin/Doxepin HCl/Indomethacin Topical Lipoderm®
Lidocaine HCl Isotonic Nasal Spray
Dichloralphenazone/Isometheptene Mucate/Acetaminophen Capsules
Ketoprofen/Cyclobenzaprine HC Topical Lipoderm® ActiveMax™ (BUD Study)
Indomethacin Topical Lipoderm®
Indomethacin Base MBK Suppository (Pink Mold)

Commonly Requested Formulas for Patients with Dizziness, Vomiting, Nausea

Lorazepam/Diphenhydramine HCl/Haloperidol/Metoclopramide Topical Lipoderm®
Ondansetron Topical Lipoderm ActiveMax®
Ondansetron Oral Effervescent
Ondansetron Oral Suspension (SuspendIt™)
Scopolamine Hydrobromide Topical Lipoderm®
Promethazine HCl Topical Lipoderm® (BUD Bracketed Study)
Ginger Root Sorbitol Lollipop Base

Commonly Requested Formulas for Patients with Insomnia

Melatonin Sublingual Suspension (MucoLox™)
Lorazepam Gelatin Troche
Lorazepam Topical Lipoderm® (BUD Study)
Tryptophan Capsules

Commonly Requested Formulas for Patients with Peripheral Neuropathy

Ketamine HCl/Gabapentin/Clonidine HCl/Baclofen Topical Lipoderm® ActiveMax™
Ketamine HCl/Gabapentin/Clonidine HCl/Baclofen Topical Lipoderm®

Commonly Requested Formulas for Patients Experiencing Drowsiness

Caffeine Sorbitol Lollipop Base
Caffeine Citrate Oral Suspension (SuspendIt™)
Yohimbine HCl Capsules

Commonly Requested Formulas for Patients with Diarrhea

Loperamide HCl Rectal Gel (MucoLox™/VersaBase®)
Hyoscyamine Sulfate Base A Troche
Hyoscyamine Sulfate Slow Release Capsules
Morphine (Anhydrous) Oral Solution
Kaolin/Pectin/Belladonna/Paregoric Oral Liquid

Commonly Requested Formulas for Patients with Dry Skin

Sodium Hyaluronate Topical Gel
Aloe Vera Topical Gel (PracaSil®-Plus)
Urea Topical Gel (PracaSil®-Plus)
Urea/ Sodium Hyaluronate/PracaSil®‐Plus Topical Gel (Spira‐Wash™)
Emu Oil/Panthenol/Bacocalmine™ PH/Dimethyl Sulfone/Sodium Hyaluronate Topical Lotion

Commonly Requested Formulas for Patients with Vaginal Dryness

Vitamin E/Vitamin A/Sodium Hyaluronate Vaginal Gel (MucoLox™/VersaBase®)
Vitamin E Vaginal Gel (MucoLox™/VersaBase®)

Commonly Requested Formulas for Patients with Increased Sweating

Glycopyrrolate Topical Solution
Glycopyrolate Topical Lotion
Aluminum Chloride Topical Solution

Commonly Requested Formulas for Patients with Dry Mouth

Pilocarpine HCl Oral Drops (MucoLox™) (BUD Study)
Artificial Saliva Gel (MucoLox™)
Pilocarpine HCl Sorbitol Lollipop Base
Sodium Chloride/Potassium Chloride/Calcium Chloride Base A Troche
Saline/Glycerin Oral Suspension
Oral Rinse ‐ General Formula (MucoLox™)
Electrolyte Saliva Gel (MucoLox™)
Supersaturated Calcium Phosphate Oral Rinse (MucoLox™)

Commonly Requested Formula for Patients with Memory Impairment

Selegiline HCl Polyglycol Troche

Commonly Requested Formulas for Patients with a Skin Rash

Betamethasone Valerate/Tranilast Topical Gel (PracaSil®-Plus)

Commonly Requested Formulas for Patients with Alopecia

Squaric Acid Dibutyl Ester Topical Solution
Diphenylcyclopropenone Topical Solution
Minoxidil/Tretinoin Topical Gel
Minoxidil Topical Solution

Commonly Requested Formulas for Patients with Pruritis

Lidocaine HCl/Diphenhydramine HCl/Dexamethasone/Cimetidine Topical Cream (VersaBase®)
Hydrocortisone/Pramoxine HCl Topical Cream
Pitch Ointment (PracaSi®‐Plus)
Diphenhydramine HCl/Pramoxine HCl/Hydrocortisone Acetate Compound Topical Gel

Side Effects of Specialty Drugs

HARVONI
Chronic Hepatitis C genotype 1 in adults
CNS: headache and fatigue
Nausea
Insomnia
Diarrhea
Increased serum lipase
Hyperbilirubinemia

OLYSIO
Chronic Hepatitis C genotype 1.
Offlabel: Chronic Hepatitis C genotype 4 and 1 for treatment naïve pts or those who cannot take peninterferon alfa
CNS: fatigue, headache, dizziness, insomnia
Derm: pruritis, skin rash (erythema, eczema, maculopapular rash, urticaria, toxic skin eruption, dermatitis, exfolatiave cutaneous vasculitis, photosensitivity reaction
GI: nausea, diarrhea
Hepatic: increased serum bilirubin
Neuromuscular/skeletal: myalgia
Respiratory: Dyspnea
Skin photosensitivity grade 3, skin rash, increased serum alkaline phosphatase

SOVALDI
Chronic hepatitis C genotype 1, 2, 3, 4 and combination HIV/HCV coinfection.
Offlabel: Chronic hepatitis C genotype 5 & 6 in treatment niave or relapse patients
CNS: chills, fatigue, headache, insomnia, irritablity
Derm: pruritis, skin rash
GI: decreased appetite, diarrhea, nausea
Hematologic/Oncologic: anemia, decreased hemoglobin, decreased neutrophils, neutropenia
Neuromuscular/skeletal: myalgia, weakness.
Respiratory: flu like symptoms,
Misc: fever
GI: increased serum lipase
Hematologic/Oncologic: Thrombocytopenia
Hepatic: Increased serium bilirubin
Neuromuscular/skeletal: increased creatine phosphokinase
<1%: pancytopenia, severe depression, suicide ideation

PEGASYS
Chronic Hepatits B & C. Offlabel: Polycythemia vera, renal cell carcinoma, chronic myelogenous leukemia, chronic Hepatitis C genotypes 1, 4, 5 or 6
CNS: anxiety, depression, dizziness, fatigue, fever, headache, insomnia, irritability, pain
Derm: alopecia, pruritis
GI: abdominal pain, anorexia, diarrhea, nausea/vomiting
Hematologic: neutropenia
Musculoskeletal: arthralgia, myalgia, rigors
Misc: injection-site reaction, pain, pyrexia, resistant mechanism disorders
Bacterial infections
CNS: memory impairment, mood alteration.
Derm: dermatitis, dry skin, eczema, increased sweating, rash.
GI: dry mouth, dyspepsia.
Hematologic: anemia, lymphopenia, thrombocytopenia.
Musculoskeletal: back pain.
Respiratory: cough, dyspnea, exertional dyspnea.
Misc: blurred vision, hypothyroidism, weight decrease

ATRIPLA
HIV-1 infection
Abnormal dreams, depression, diarrhea, dizziness, fatigue, headache, hypercholesterolemia, insomnia, nausea, rash
CNS: anxiety
Derm: rash
GI: vomiting
Respiratory: nasopharyngitis, sinusitis, upper respiratory tract infections

ISENTRESS
HIV-1 infection Offlabel: postexposure prophylaxis for occupational exposure to HIV
Endocrine: increased serum glucose
Hepatic: increased serum ALT/AST
CNS: dizziness, fatigue, headache, insomnia
GI: increased serum amylase, increased serum lipase, nausea
Hematologic/oncologic: abnormal ANC, thrombocytopenia
Hepatic: hyperbilirubinemia, increased serum alkaline phosphatase
Neuromuscular/skeletal: increased creatine phosphokinase

PREZISTA
HIV-1 infection
Endocrine/Metabolic: hypercholesterolemia, increased LDL.
GI: diarrhea, nausea, vomiting
CNS: fatigue, headache
Derm: pruritus, skin rash
Endocrine/Metabolic: diabetes mellitus, hyperglycemia, increased amylase, increased serum triglycerides
GI: abdominal distension, abdominal pain, anorexia, decreased appetite, dyspepsia, increased serum lipase
Hepatic: Increased serum ALT/AST and increased serum alkaline phosphatase

REYATAZ
HIV-1 infection
Derm: skin rash
Endocrine/Metabolic: increased amylase, increased serum cholesterol GI: Nausea, vomiting
Hematologic/Oncologic: neutropenia
Hepatic: increased serum ALT, increased serum bilirubin, jaundice
Neuromuscular/skeletal: increased creatine phosphokinase
Respiratory: cough
Misc: fever
Cardiovascular: first and second degree artrioventricular block, edema
CNS: depression, dizziness, headache, insomnia, peripheral neuropathy Endocrine/metobolic: hyperglycemia, hypoglycemia, increased serum triglycerides
Hematologic/oncologic: decreased hemoglobin, thrombocytopenia.
Hepatic: increaded AST
Neuromuscular/skeletal: limb pain, myagia
Respiratory: nasal congestion, oropharyngeal pain, rhinorrhea, wheezing

STRIBILD
HIV-1 infection
GI: diarrhea, nausea
Genitourinary: proteinuria
CNS: abnormal dreams, dizziness, drowsiness, fatigue, headache, insomnia Derm: skin rash
Endocrine/metabolic: increased amylase, increased serum cholesterol, incrased serum triglycerrides GI: flatulence
Genitourinary: hematuria
Hepatic: increased serum AST
Neuromuscular/skeletal: bone fracture, increased creatine phosphokinase
Renal: increased serum creatinine

TRUVADA
Preexposure prophylaxis for sexually acquired HIV-1, Treatment for HIV-1. Offlabel: preexposure prophylaxis for HIV-1 infection for IV drug users and occupational exposure, treatment for antiviral resistant Hepatitis B or coinfection with HIV
abnormal dreams, depression, diarrhea, dizziness, fatigue, headache, insomnia, nausea, skin rash
GI: vomiting
Respiratory: nasopharygnitis, sinusitis, upper respiratory tract infection

CIMZIA
Ankylosing spondylitis, crohn disease, psoriatic arthritis, rheumatoid arthritis
GI: nausea. Infection. Resipiratory: upper respiratory infection.
Cardiovascular: angina pectoris, atrial fibrillation, cardiac arrhythmia, cardiac failure, cerebrovascular accident, hypertension, hypertensive heart disease, ischemic heart disease, myocardial infarction, pericardial infusion, pericarditis, thrombophlebitis, transient ischemic attacks, vasculitis
CNS: anxiety, bipolar mood disorder, fatigue, headache, suicidal tendencies
Derm: alopecia, dermatitis, erythema nodosum, skin rash, uticaria
Endocrine/metabolic: menstrual disease
Genitourinary: nephrotic syndrome, UTI
Hematologic/oncologic: anemia, hemorrhage, hypercoagubility state, leukpenia, lymphadenopathy, pancytopenia, positive ANA titer Hepatic: hepatitis, increased serum transaminases
Immunologic: antibody development
Neuromuscular/skeletal: arthralgia, back pain
Ophthalmic: optic neuritis, retinal hemorrhage, uveitis
Renal: renal failure
Respiratory: bronchitis, cough, nasopharyngitis, pharyngitis, tuberculosis Misc: fever

ENBREL
Ankylosing spondylitis, plaque psoriasis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, rheumatoid arthritis. Offlabel: graft vs host disease, hidradenitis suppurativa, idiopathic thrombocytopenia purpura, nephrotic syndrome, pyoderma gangrenosum, uveitis, wegener granulomatosis
CNS: headache
Derm: skin rash
GI: abdominal pain, diarrhea, vomiting
Hematologic/oncologic: positive ANA titer Immunologic: antibody development
Infection
Local: injection site reaction
Respiratory: respiratory tract infection, rhinitis, upper respiratory tract infection
CNS: dizziness
Derm: pruritis
GI: dyspepsia, nausea
Neuromuscular/skeletal: weakness
Respiratory: cough, pharyngitis, respiratory distress, sinusitis Misc: fever

HUMIRA
Ankylosing spondylitis, crohn disease, juvenile idiopathic arthritis, plaque psoriasis, psoriatic arthritis, rheumatoid arthritis, ulcerative colits. Offlabel: pyoderma gangrenosum, uveitis.
CNS: headache.
Derm: skin rash.
Hematologic/oncologic: positive ANA titer. Immunologic: antibody development. Local: injection site reaction. Neuromuscular/skeletal: increased creatine phosphokinase. Respiratory: sinusitis, upper respiratory tract infection.
Cardiovascular: atrial fibrillation, cardiac arrest, cardiac arrythemia, cardiac failure, chest pain, coronary artery disease, deep vein thrombosis, hypertension, hypertensive encephalopathy, myocardial infarction, palpitations, pericardial effusion, pericarditis, peripheral edema, subdural hematoma, syncope, tachycardia, vascular disease. CNS: confusion, myasthenia, parasthesia
Derm: Alopecia, cellulitis, erysipelas
Endocrine/metabolic: dehydration, hypercholesterolemia, hyperlipidemia, ketosis, mentrual disease, parathyroid disease
GI: abdominal pain, cholecystitis, cholelithiasis, diverticulitis, esophagitis, gastroenteritis, gastrointestinal hemorrhage, nausea, vomiting
Genitourinary: cystitis, hematuria, pelvic pain, urinary tract infection Hematologic/oncologic: adenoma, agranulocytosis, carcinoma, granulocytopenia, luekopenia, malignant lymphoma, malignant melanoma, pancytopenia, paraproteinemia, polycythemia
Hepatic: hepatic necrosis, increased serum alkaline phosphatase
Hypersensitiviy reaction Infection: herpes zoster, sespis, serious infection
Neuromuscular/skeletal: arthralgia, arthritis, arthropathy, back pain, bone fracture, limb pain, multiple sclerosis, muscle cramps, osteonecrosis, septic arthritis, synovitis, systemic lupus erythematosus, tendon disease, tremor Ophthalmic: cataract
Renal: nephrolithiasis, pyelonephritis
Respiratory: asthma, bronchospasm, dyspnea, flu-like symptoms, pleural effusion, pneumonia, respiratory depression, tuberculosis
Misc: abnormal healing, accidental injury, fever, post operative complication (infection)

SIMPONI
Ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, ulcerative colitis
Hematolgic/oncologic: Positive ANA titer Infection
Respiratory: upper respiratory tract infection
Cardiovascular: hypertension
CNS: dizziness, parathesia
Derm: skin rash
GI: constipation
Hematologic/oncologic: leukopenia
Hepatic: Increased AST/ALT
Immunologic: antibody development
Infection: bacterial infection, fungal infection, serious infection, viral infection Local: injection site reaction
Respiratory: bronchitis, sinusitis
Misc: fever, infusion related reaction

STELARA
Plaque psoriasis, psoriatic arthritis
Infection
CNS: depression, dizziness, fatigue, headache
Derm: pruritus
GI: nausea
Immunlogic: antibody development
Infection: severe infection
Local: erythema at injection site
Neuromuscular/skeletal: arthralgia, back pain Respiratory: pharyngolaryngeal pain